Wang Xinluan, researcher and doctoral supervisor. Since May 2011, he has worked in Shenzhen Advanced Technology Research Institute of the Chinese Academy of Sciences.

Mainly engaged in basic and translational medicine research on the treatment of musculoskeletal system diseases with traditional Chinese medicine and natural medicines, including the exploration of molecular mechanisms and potential targets for the treatment of osteoporosis, osteoarthritis, sarcopenia, and osteonecrosis; And the research and development of new drug containing bone/cartilage repair materials, as well as bone/cartilage regeneration and transformation.

Wang Xinluan is a review expert for projects funded by the National Natural Science Foundation of China, Guangdong Province Science and Technology Project, and Shenzhen City Science and Technology Project, and is a provincial-level talent in Guangdong Province.

Wang Xinluan has long focused on the scientific interpretation and innovative product development of traditional Chinese medicine in the treatment of bone diseases. He focuses on the scientific issues of unclear functional ingredients and mechanisms of action in compound Chinese medicine, as well as new propositions in the development of innovative Chinese medicine drugs. Combining traditional Chinese medicine theory with modern scientific technology, he has systematically conducted comprehensive research on the efficacy, ingredients, mechanisms of action, and safety of large varieties of Chinese medicine, revealing the scientific connotation of its material basis and mechanism of action in the treatment of bone diseases. On this basis, additive manufacturing technology was used to develop a combination of medicinal and mechanical products containing active ingredients of traditional Chinese medicine, in order to achieve bone/cartilage tissue regeneration in degenerative bone diseases and explore a new direction in the field of traditional Chinese medicine tissue engineering scaffolds. We plan to propose a new concept of using traditional Chinese medicine to treat osteoporosis and fractures simultaneously, and explore new directions for innovation in traditional Chinese medicine. Hosted more than 10 provincial and ministerial level projects, including the National Natural Science Foundation General Project, the Ministry of Science and Technology's National International Cooperation Special Project, the National Key Research and Development Program (Strategic Science and Technology Innovation Cooperation Special Project), the National Key Research and Development Program (Project), and the Guangdong Province Basic Research Key Project; Cooperating with enterprises such as China National Pharmaceutical Group, Xianle Health, Step Group, and Anjisheng Biotechnology to carry out research and development projects on traditional Chinese medicine and innovative drugs, and obtaining horizontal funding of over ten million yuan; Published 120 papers with an H-Index of 41, cited nearly 4000 times in the past 5 years; Authorized 15 invention patents and 1 technology transformation; Received the second prize for scientific and technological progress from the Ministry of Education as a completion person; COA Orthopedic Basic Youth Research Third Prize; Silver/Excellent Award of China Patent Award; Second Prize of Shenzhen Technology Invention Award; China Pharmaceutical Development Award Kangchen Osteoporosis Medicine Research Award Outstanding Young Scholar Award.

1. Jian Zou, Zuocheng Qiu, Qiangqiang Yu, Jiaming Wu, Yongheng Wang, Keda Shi, Yifang Li, Rongrong He, Ling Qin, Xinsheng Yao, Xinluan Wang*, Hao Gao*. Discovery of a potent antiosteoporotic drug molecular scaffold derived from Angelica sinensis and its bioinspired total synthesis. ACS Central Science (2024) 10: 628-636.

2. Xiangbo Meng, Ling Li, Cuishan Huang, Keda Shi, Qingqiang Zeng, Chunyi Wen, Sibylle Grad, Mauro Alini, Ling Qin*, Xinluan Wang*. Anti-inflammatory and Anabolic Biphasic Scaffold Facilitates Osteochondral Tissue Regeneration in Osteoarthritic Joints. Journal of Materials Science & Technology (2023) 156: 20-31.

3. Wenyao Yang, Bimin Gao, Ling Qin, Xinluan Wang*. Puerarin improves skeletal muscle strength by regulating gut microbiota in young adult rats. Journal of Orthopaedic Translation (2022) 35: 87-98.

4. Yanzhi Liu, Liuqi Peng, Lingli Li, Cuishan Huang, Keda Shi, Xiangbo Meng, Pingping Wang, M. Wu, L. Li, Huijuan Cao, K. Wu, Qingqiang Zeng, Haobo Pan, William Weijia Lv, Ling Qin, Changshun Ruan*, and Xinluan Wang*, 3D-bioprinted BMSC-laden biomimetic multiphasic scaffolds for efficient repair of osteochondral defects in an osteoarthritic rat model. Biomaterials (2021) 279: 121216.

5. Huijuan Cao, Keda Shi, Jing Long, Yanzhi Liu, Lingli Li, Tianluo Ye, Cuishan Huang, Yuxiao Lai, Xueling Bai, Ling Qin*, Xinluan Wang*. PDGF-BB prevents destructive repair and promotes reparative osteogenesis of steroid-associated osteonecrosis of the femoral head in rabbits. Bone (2022) 167: 116645.